Isomalt

Functional Category

Coating agent; granulation aid; medicated confectionary base;

sweetening agent; tablet and capsule diluent.

Applications in Pharmaceutical Formulation or

Technology

Isomalt is a noncariogenic excipient used in a variety of pharmaceutical preparations including tablets or capsules, coatings, sachets, and suspensions, and in effervescent tablets. It can also be used in direct compression and wet granulation.

In buccal applications such as chewable tablets it is commonly used because of its negligible negative heat of solution, mild sweetness, and ‘mouth feel’.  It is also used widely in lozenges, sugar-free chewing gum, and hard-boiled candies, and as a sweetening agent in confectionery for diabetics.

Isomalt is a sugar alcohol (polyol) that occurs as a white or almost white powder or granular or crystalline substance. It has a pleasant sugarlike taste with a mild sweetness approximately 50–60% of that of sucrose.

Isomalt is produced from food-grade sucrose in a two-stage process. Beet sugar is converted by enzymatic transglucosidation into the reducing disaccharide isomaltulose. This undergoes catalytical hydrogenation to produce isomalt.

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